MEDULLOBLASTOMA IN A 16-YEAR-OLD PATIENT: A CLINICAL CASE

Relevance: Brain tumors are children’s most common solid tumors, with medulloblastomas accounting for almost 20%. The Electronic
 Registry of Oncological Patients the Republic Kazakhstan (RK) reports 27 morphologically verified cases medulloblastoma in
 2021, 18 them in children (66.6%).
 aim was to show feasibility conducting a molecular genetic study clarify diagnosis brain using clinical
 case as an example.
 Methods: article describes clinical patient medulloblastoma. examinations included computed tomography
 brain, magnetic resonance imaging and pathomorphological revision immunohistochemical examination of
 postoperative material.
 Results: admitted Center Pediatric Oncology “Kazakh Institute Radiology” JSC
 (Almaty, Kazakhstan) referral morphological “Ependymoma cerebellar vermis compression the
 4th ventricle. Grade II. Condition – after ventricular operitoneostomy on left side (14.11.2021), microsurgical removal tumor (07.12.2021). 2nd group.” Because atypical localization formation, review with
 material carried out. Conclusion: picture immunophenotype correspond desmoplastic/nodular medulloblastoma, grade IV. ICD-O code 9471/3. treatment tactics were revised
 based data.
 Medulloblastoma is highly malignant aggressive course. Choosing right depends timely, accurate diagnosis, which makes critical link management algorithm. In addition, it
 requires examination. According 5th version 2021 WHO classification CNS required accurately determine structure and
 achieve better response therapy. it necessitates relevant guidelines adopted Republic